Job Description
Title: Senior Research Associate/Scientist
Location: Hayward, Ca (on-site)
Reports to : Group Leader ADME at Quintara Discovery, part of Global Drug Discovery Services at Frontage Labs
Classification : Full-time
Frontage Laboratories Inc. is an award winning, publicly listed (HKSE), full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China, and growing over 30% YOY. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Position/Job Summary:
We are looking for a highly motivated Senior Research Associate or Entry level Scientist (DOE) to develop and conduct pre-clinical Absorption, Distribution, Metabolism, and Excretion (ADME) parameter determination assays to evaluate potential therapeutics. Assay requests range from standard screening assays used to determine ADME properties of pharmaceutical candidates to developing and validating definitive assays from scratch following literature review. Standard assays include solubility determination (kinetic and thermodynamic), tissue and enzyme stability (microsomes, hepatocytes, plasma, blood, etc), phenotyping, protein binding (RED, HTPB, and ultracentrifugation), permeability, tissue partitioning, enzyme/transporter substrate/inhibitor determination and many others. We also employ robotic automation, HPLC and LC-MS/MS-based data analysis to enable high throughput screening. This position works with an interdisciplinary team of DMPK scientists, pharmacologists, and analytical chemists. It is lab-based, collaborative, and client-facing. While delivering accurate, scientifically sound results is our priority, we pride ourselves in being exceptionally responsive and flexible for our clients, using creativity and efficiency to meet their drug discovery goals.
Roles & Responsibilities:
Education, Experience & Skills Required:
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
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